Viscosupplement Injections


Euflexxa is a treatment for OA knee pain and is safe to use with over-the-counter pain medications or physical therapy. Euflexxa is a gel-like, natural, and highly purified form of HA. HA is a natural substance found in the fluid that cushions, lubricates, and protects the knee. In people with OA of the knee, this fluid is thinner and less able to do its job.

Euflexxa is the HA therapy that is most similar to the HA found in healthy knees. When Euflexxa is injected into the knee, it replenishes the HA in the fluid around the knee, helping restore its ability to cushion, lubricate, and protect the knee.

How can Euflexxa Help:

  • Euflexxa can provide significant reductions in pain.
  • Euflexxa can help people better perform everyday activities.
  • Euflexxa is proven to work in just 3 injections (once a week for 3 weeks).


Synvisc – One:

Synvisc-One® (hylan G-F 20) is a viscosupplement injection. Made from a natural substance that lubricates and cushions your joint, it can provide up to six months of osteoarthritis knee pain relief with just one injection.

What is Synvisc-One?

Synvisc-One: Diagram 1Synvisc-One: Diagram 2

In knees with osteoarthritis, the joint fluid (called synovial fluid) can break down and not provide the cushioning your knee needs.

Synvisc-One supplements your knee joint fluid to relieve the pain and improve the knee joint’s natural shock absorbing abilities.

A. Cartilage wears away
B. Bone spurs may develop
C. Joint fluid breaks down
D. Synvisc-One replaces joint fluid

Who is a candidate for Synvisc-One?:
Patients with knee osteoarthritis who have tried diet, exercise and over-the-counter pain medication but still have pain, should talk to their doctor to see if Synvisc-One is right for them.

How Synvisc-One is Administered:
Synvisc-One is a single injection. It’s a simple, in-office procedure that only takes a few minutes.

What you can expect following a Synvisc-One knee injection?:
Synvisc-One can provide up to six months of osteoarthritis knee pain relief. Everyone responds differently, but in a medical study* patients experienced relief starting one month after the injection.

After the injection, you can resume normal day-to-day activities, but you should avoid any strenuous activities for about 48 hours.

Synvisc-One® (hylan G-F 20) can provide up to six months of osteoarthritis knee pain relief with a single injection. In order to determine how well Synvisc-One reduced osteoarthritis knee pain during five common activities (walking on a flat surface, going up stairs, resting during the night, sitting or lying down, and standing upright), a medical study* was conducted and the side effects were tracked.

Pain relief results with Synvisc-One:
The study showed that patients who received Synvisc-One had significantly less osteoarthritis knee pain over six months and felt significantly better than the saline control group. Most patients reported pain relief starting at week four.

Side effects with Synvisc-OneL:
Since Synvisc-One is injected directly into the knee, it doesn’t have the serious side effects found with many pain pills.

The side effects most commonly seen in the medical study were knee pain, stiffness and swelling or fluid buildup in or around the knee. Side effects were generally mild to moderate and did not last long.

The types and frequencies of side effects were similar between the Synvisc-One and the saline control groups. No serious side effects were seen in the injected knee during the study that were related to the use of Synvisc-One.

  • Contact Us:

    Trinity Sports Medicine
    & Performance Center

    3151 Johnson Rd, Suite 2
    Steubenville, OH 43952

    Dr. Scarpone: 740-266-3866
    Physical Therapy: 740-266-3872

    Got a question: Contact Us
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